The special period of 21 days before delivery and 15 days after delivery is called the perinatal period. During this period, cows undergo a series of complex physiological processes such as pregnancy, childbirth, and lactation. The changes and adjustments to the body's nutritional and endocrine functions are very intense. It leads to a decline in the immune status and disease resistance of dairy cows, so it is often referred to as the pathological stage of dairy cows. If there is a problem with feeding management, it will induce various diseases such as puerperal fever, ketosis, restlessness, metritis, laminitis, displacement of the true stomach, and mastitis.
Glucose oxidase enzyme is green and safe food-grade biological enzyme preparation obtained by fermentation of specific Aspergillus fungi strains and advanced purification technology. It is widely used in food, medicine, feed, and other industries. Under aerobic conditions, β-D-glucose can be highly specifically catalyzed to produce gluconic acid and hydrogen peroxide.
(1) Catalyze glucose in the intestine to produce gluconic acid and hydrogen peroxide. When hydrogen peroxide accumulates to a certain concentration, it inhibits the growth and reproduction of harmful bacteria, such as Escherichia coli and Salmonella.
(2) Catalyze glucose to remove oxygen in the intestinal tract, creating an anaerobic environment for the proliferation of anaerobic beneficial bacteria. Eliminate a large number of free radicals produced by intestinal epithelial cells when animals are under stress, protect the integrity of intestinal epithelial cells, and inhibit the invasion of coccidia and pathogenic bacteria.
(3) The produced gluconic acid acts as an acidifier in the intestine, creating an acidic environment, lowering the pH value in the stomach, activating pepsin, stimulating the growth of lactic acid bacteria, etc., enhancing the digestion and absorption of nutrients in the intestine, and reducing diarrhea.
(4) Glucose oxidase enzyme creates an acidic environment for the growth of beneficial bacteria, and the proliferation of beneficial bacteria forms a micro-ecological competitive advantage, which inhibits the survival of harmful bacteria such as Escherichia coli and Salmonella. Control infection, eliminate spoilage and improve macrophage activity, thereby enhancing the body's immunity.
After the glucose oxidase enzyme enters the rumen, the glucose oxidase enzyme consumes oxygen in the process of interacting with glucose, causing the digestive tract to form an anaerobic environment and quickly restore the normal anaerobic environment in the rumen. Reproduce beneficial microorganisms, restore the ecological balance of the flora, promote the fermentation and decomposition of roughage, and reduce the production of toxic substances. At the same time, as an oxidoreductase, it assists the liver to metabolize toxins, relieves the inhibition of toxic substances on the reflex activity of the digestive tract, and promotes the normal peristalsis of the front stomach. Glucose oxidase enzyme can effectively relieve the common loss of appetite caused by the perinatal period, calf changing grass, and diseases. It also has the effects of preventing remnants, reducing the occurrence of metabolic diseases, and improving long-term indigestion in dairy cows.
The suggested dosage of glucose oxidase enzyme: twice a day, 150g solid (150ml liquid) mixed in feed or 200ml mixed in drinking water. After observing that the main symptoms are reduced, such as appetite, stool color, etc., the dosage can be reduced by 50% as appropriate.
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