Bestzyme is pleased to announce a flagship product Mellia™ Brazzein, has officially received the “No Questions” letter from the U.S. Food and Drug Administration (FDA) regarding its GRAS (Generally Recognized as Safe) status. The GRAS designation recognizes it as general-purpose sweetener for a wide range of applications in the food and beverage industry.

This milestone follows the successful Self-GRAS certification completed in early July 2024. It marks the official FDA approval of Mellia™ Brazzein, affirming the product’s safety and regulatory compliance. With this GRAS approval, Bestzyme has received international recognition for its innovative breakthrough in the natural sweetener industry.

Brazzein is a naturally occurring sweet protein found in the fruit of the West African plant Oubli (Pentadiplandra brazzeana Baillon). Now, Bestzyme has enabled its sustainable and industrial-scale production through precision fermentation.

Mellia™ Brazzein features pure sweet taste, high sweetness and flavor modifying function. As a next-generation, high-quality sweetener, it is ideal for sugar-reduction solutions across a wide range of applications, including beverages, dairy products, confectionery, chocolate, health supplement, and catering.

Mellia™ Brazzein has the molecular structure of a protein and can be rapidly digested into amino acids in the human body, without raising blood glucose or disrupting the gut microbiome. With growing emphasis on health-conscious lifestyles, the market is increasingly demanding sugar-reduction solutions. Mellia™ Brazzein meets this need by offering a zero-calorie sweetener that does not impact blood sugar levels, empowering consumers to make healthier dietary choices.

As global demand for sugar reduction continues to grow, the market for sugar-reducing ingredients is expanding rapidly, catalyzed by technological innovation in food industry. Regulatory approval empowers Bestzyme’s Mellia™ Brazzein to confidently enter the global sweet market.

Looking ahead, Bestzyme regards Mellia™ Brazzein as a milestone in its new functional protein product pipeline. The company is committed to advancing the frontiers of biology, developing a robust portfolio of high-value products, and empowering global consumers with healthier, sustainable choices. By leveraging bio-based innovations, it aims to drive green manufacturing practices and contribute to building a more sustainable future.

Product Contact:

Iris Jiang
Senior BD Manager
Email: [email protected]